GeneTalk with Dr. Misbah

Breast Cancer Awareness Camp 2026
The Department of Surgical Oncology, Dow University of Health Sciences, is organizing a Breast Cancer Awareness Camp 2026 with the aim of taking awareness and early detection beyond hospital walls and into the community.
Date: 8 October 2026 | Thursday
Time: 10:00 AM - 12:00 PM
Venue: Roshan Tara School, Sachal Goth, Karachi Early detection saves lives. Let's spread awareness, encourage timely consultation, and work together towards better breast health.
#BreastCancerAwareness
#BreastCancerAwarenessCamp #BreastCancer #DUHS

1 month ago | [YT] | 4

GeneTalk with Dr. Misbah

One letter can change everything. Help us find it.
Somewhere, right now, a kid is sick and nobody knows why.
Their parents have seen a dozen doctors. Run every test.
Nobody has an answer.
But that answer might already exist, buried in three billion letters of their DNA, waiting for someone to actually look closely enough to find it.
That's not science fiction. That's just genetics. And it's a job that's too big for scientists to do alone.
That's where you come in.
What is #GenomeNation?
We're a free, global community teaching anyone - no science degree, no lab coat, no prerequisites; on how to read DNA and spot the difference between a harmless typo and one that actually makes someone sick.
You'll learn the real method real genetic experts use. Not a simplified version. The actual thing.
Then you'll practice on real, unsolved genetic mysteries; the kind sitting in databases right now, waiting for someone with fresh eyes.
You don't need to already be smart about genetics. You just need to be curious enough to look twice.
Why this actually matters
Right now, there are hundreds of thousands of these DNA mysteries sitting unsolved. Too many, not enough people trained to solve them.
Every single one you help crack could be:
A diagnosis a family has waited years for A faster path to the right treatment
A future drug that gets built because someone finally understood what they were fighting
This isn't a small thing. This is literally how humanity gets better at understanding itself — one variant, one volunteer, one "wait, I think I found something" at a time.
You could be part of the generation that made genetics make sense for everyone, not just the people who can afford a specialist.
Here's the honest pitch
You'll get real training. A real credential. A real community of people across the world doing this alongside you.
But more than that, you'll get to say you were part of something that actually mattered. Not an internship that filled a summer. A movement.
The genome doesn't read itself.
We can do it together
Join #GenomeNation Inkd.in/gMvVzPgq

2 months ago | [YT] | 6

GeneTalk with Dr. Misbah

A genetic report can look intimidating.

For a clinician who understands genomics, however a genomic report can become a powerful clinical tool, helping connect diagnosis, prognosis and treatment.
#genetics #diagnosis #medicine

2 months ago | [YT] | 8

GeneTalk with Dr. Misbah

DNA Screening Could Prevent More Diseases in Asian Populations

A study of nearly 4,000 people in Taiwan found that whole genome sequencing can identify inherited health risks that many people don't know they have. Almost half of those with genes linked to inherited high cholesterol were undiagnosed. Researchers also found important genetic changes common in East Asians that are not included in standard screening. The findings suggest population-specific DNA testing could improve early detection and prevention of disease.

3 months ago | [YT] | 9

GeneTalk with Dr. Misbah

You carry more genetic variants than you imagine
Here's a fact most people don't know.
Every person carries around 4-5 million DNA differences compared with the reference genome.
Almost all are harmless.
Only a tiny fraction affect health.
Modern genome analysis is like finding a few important pages in a library of millions of books.
The challenge isn't sequencing DNA anymore.
It's understanding what matters.
That's where genomic #genetics #genomics #science #dna #inheriteddisorders #gene

3 months ago | [YT] | 7

GeneTalk with Dr. Misbah

With the advancement of NGS, we are identifying thousands of variants. But the biggest challenge is not just finding a variant, it is understanding its clinical relevance.
A common misconception in genomics:
"Pathogenic variant = confirmed diagnosis."
But in clinical genetics, a variant cannot be interpreted in isolation.
A meaningful diagnosis requires connecting multiple pieces of evidence:
Patient phenotype -does the clinical presentation
match the gene and disease spectrum?
Inheritance pattern - does segregation support the
suspected condition?
Variant mechanism - does the variant type explain the
known disease mechanism?
Gene-disease validity - how strong is the evidence
linking the gene to the phenotype?
Literature & population evidence - what do current
databases and studies tell us?
A pathogenic variant in a gene that does not explain the clinical picture may create more questions than answers.
This is why genotype-phenotype correlation remains the cornerstone of genomic medicine.
Sequencing gives us the data.
Interpretation gives us the diagnosis.
Because in genetics, we don't just interpret variants, we understand patients.
#genetics #geneticcounseling #genetictesting #carriergeneticscreening #inheriteddiseases #pakistan #drmisbah #rarediseases #genomics #education #awareness #diagnosis #dna #childhealth #pregnancy

3 months ago | [YT] | 7

GeneTalk with Dr. Misbah

A remarkable milestone in medical science!
• A baby has been born through a groundbreaking three-person DNA procedure, marking a major step toward preventing inherited mitochondrial diseases.
While the baby received almost all of their DNA from
their biological parents, a small amount of healthy mitochondrial DNA from a donor may help prevent serious genetic disorders.
This breakthrough builds on years of research in mitochondrial replacement therapy, with significant contributions from scientists including Dr. Mary Herbert, Dr. Doug Turnbull, Dr. Shoukhrat Mitalipov, and Dr. John Zhang.
• It offers new hope for families affected by rare mitochondrial conditions while also encouraging important discussions about the future of genetic medicine, ethics, and innovation.
As science continues to push boundaries, each breakthrough brings the incredible opportunities and important responsibilities.
#genomics #genetics #mitochondrialdisease # geneticcounseling #newborn #breakingnews #science

3 months ago | [YT] | 8

GeneTalk with Dr. Misbah

Not every patient needs the biggest genetic test. The best test is the one that answers the right clinical question.
Choosing the appropriate genomic test improves diagnosis, reduces unnecessary costs, and helps clinicians make better decisions for their patients.
Genetics isn't about ordering more tests—it's about asking the right questions.
🧬 Follow for evidence-based genetics content made simple.
#genetics #genomictesting #clinicalgenetics #RareDisease #MedicalEducation #Healthcare #MolecularDiagnostics #Pakistan

4 months ago | [YT] | 11

GeneTalk with Dr. Misbah

* Applications Open!
Join the Summer Internship Program 2026 - Molecular Genetics & Genomics at DOW-DOGANA, DUHS Karachi.
• Hands-on training | 2
Advanced genomics exposure |
17
Deadline: 29 June 2026
#Genomics #Internship #DUHS #Research #Biotechnology #NGS #Training #Molecularmedicine

4 months ago | [YT] | 11

GeneTalk with Dr. Misbah

Pakistan begins work on national genomic policy

Pakistan has begun work on a National Genomic Policy aimed at disease prevention and stronger health security. Officials and experts highlighted the burden of inherited disorders and outlined plans for screening, surveillance and local diagnostic capacity.ISLAMABAD: Pakistan has started work on a National Genomic Policy intended to strengthen disease prevention and improve health security, as the Ministry of National Health Services, Regulations and Coordination and the Health Services Academy held a high-level consultative meeting on the proposed framework.

The session brought together Pakistani and international specialists in genomics, genetics, molecular biology, public health and health policy. Participants included experts from Aga Khan University, Quaid-i-Azam University, the Centre of Excellence in Molecular Biology in Lahore, and the Massachusetts Institute of Technology in the United States. Those attending described the proposed policy as an important step for the country’s healthcare system.

www.pakistantoday.com.pk/2026/06/12/pakistan-begin…

4 months ago | [YT] | 10