The Carnivore Diet and Cardiovascular Disease Risk: A Narrative Review
We investigated the little research we have on carnivore diets and how they may impact heart health, mortality risk, nutrient intake, and more. Here’s what we found:
The evidence base is thin: There are zero randomized trials or prospective cohort studies. What exists is mostly self-reported surveys (carnivores love these, right?), case reports, and diet modeling.
The “benefits” are self-reported and short-term: People report weight loss, better glycemic control, and lower triglycerides. But these come from self-selected survey respondents, with no control group, and they’re largely unverified. They also coincide with cutting out ultra-processed foods, so they can’t be attributed to eating high amounts of meat per se. Even taken at face value, these are short-term effects. No studies have examined cardiovascular events (e.g., heart attacks/strokes).
LDL-cholesterol was markedly high on the diet: In the largest survey (2,029 adults), median LDL was self-reported as 172 mg/dL, up from 126 before the diet. A second survey showed LDL going from 157 to 256 mg/dL. LDL is a causal risk factor for atherosclerotic cardiovascular disease.
Concerning nutrient intake: Modeled carnivore menus provided zero fiber, little vitamin C, magnesium, and potassium, saturated fat at 26-32% of calories, and sodium of 7,200-8,789 mg/day.
Contradicts dietary guidance for heart health: Fruit and vegetable consumption is consistently associated with improved health outcomes across populations whilst high saturated fat and red meat intake (at doses well below what carnivores achieve) are typically associated with poorer health outcomes. While we do not have long-term prospective research on an exclusively carnivore dietary pattern, extrapolating from what is known about intakes of the various food groups/nutrients, it is reasonable to suspect long-term harm from following a diet devoid of healthy plant foods and enriched with less healthy food groups.
Mark Messina, Martha Belury, David Goldman, and I reviewed virtually every major claim behind the seed oil hysteria in this NEW review!
SPOILER: the evidence doesn’t support the fear. The controversy is largely social media-driven, built on ecological correlations, mechanistic speculation, and flawed trials, while stronger data suggests seed oil consumption may lower risk of noncommunicable diseases, including CVD, particularly when replacing saturated fat. This topic is a case study in how weak evidence gets amplified in the social media landscape.
After our debate, ‪@AmanDuggal‬ posted a recap video in which he essentially repeated the arguments from the debate, which he had already conceded on. He also dishonestly recounted what he had previously said about me.
As such, I’ve commented and laid out a more accurate recounting, as well as an offer for round 2 of the debate. The ball is in his court.
If you’ve enjoyed my videos and want to support the work I’m doing, memberships are one way to do that. Members get a few small perks like early access to some videos, member-only polls and updates, and priority replies to comments.
The main goal, though, is simply to give people who want to support the channel a way to help. I appreciate everyone who watches, shares, and engages with the content, and memberships are just another way to be part of the community.
In this video, ‪@DoctorBoz‬ said she would like to debate me on nutrition. I have been trying to comment and take her up on that but my comments are not showing. I don’t know if she has pre-emptively hidden me from commenting or it’s a YouTube issue. That said, feel free to encourage her to follow through on this via commenting.
UPDATE: it was a YouTube issue and I am now able to comment. You can go and like/boost my comment.
Dr. Matthew Nagra, ND
🚨 NEW PUBLICATION🚨
The Carnivore Diet and Cardiovascular Disease Risk: A Narrative Review
We investigated the little research we have on carnivore diets and how they may impact heart health, mortality risk, nutrient intake, and more. Here’s what we found:
The evidence base is thin: There are zero randomized trials or prospective cohort studies. What exists is mostly self-reported surveys (carnivores love these, right?), case reports, and diet modeling.
The “benefits” are self-reported and short-term: People report weight loss, better glycemic control, and lower triglycerides. But these come from self-selected survey respondents, with no control group, and they’re largely unverified. They also coincide with cutting out ultra-processed foods, so they can’t be attributed to eating high amounts of meat per se. Even taken at face value, these are short-term effects. No studies have examined cardiovascular events (e.g., heart attacks/strokes).
LDL-cholesterol was markedly high on the diet: In the largest survey (2,029 adults), median LDL was self-reported as 172 mg/dL, up from 126 before the diet. A second survey showed LDL going from 157 to 256 mg/dL. LDL is a causal risk factor for atherosclerotic cardiovascular disease.
Concerning nutrient intake: Modeled carnivore menus provided zero fiber, little vitamin C, magnesium, and potassium, saturated fat at 26-32% of calories, and sodium of 7,200-8,789 mg/day.
Contradicts dietary guidance for heart health: Fruit and vegetable consumption is consistently associated with improved health outcomes across populations whilst high saturated fat and red meat intake (at doses well below what carnivores achieve) are typically associated with poorer health outcomes. While we do not have long-term prospective research on an exclusively carnivore dietary pattern, extrapolating from what is known about intakes of the various food groups/nutrients, it is reasonable to suspect long-term harm from following a diet devoid of healthy plant foods and enriched with less healthy food groups.
Full paper: www.lidsen.com/journals/rpn/rpn-06-04-026
3 weeks ago | [YT] | 167
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Dr. Matthew Nagra, ND
This is an excellent breakdown of the methodological issues with the Keto CTA study (featured in The Cholesterol Code documentary)
3 months ago | [YT] | 22
View 2 replies
Dr. Matthew Nagra, ND
🚨ICYMI🚨
Mark Messina, Martha Belury, David Goldman, and I reviewed virtually every major claim behind the seed oil hysteria in this NEW review!
SPOILER: the evidence doesn’t support the fear. The controversy is largely social media-driven, built on ecological correlations, mechanistic speculation, and flawed trials, while stronger data suggests seed oil consumption may lower risk of noncommunicable diseases, including CVD, particularly when replacing saturated fat. This topic is a case study in how weak evidence gets amplified in the social media landscape.
Full review: www.tandfonline.com/doi/full/10.1080/10408398.2026…
6 months ago | [YT] | 112
View 2 replies
Dr. Matthew Nagra, ND
After our debate, ‪@AmanDuggal‬ posted a recap video in which he essentially repeated the arguments from the debate, which he had already conceded on. He also dishonestly recounted what he had previously said about me.
As such, I’ve commented and laid out a more accurate recounting, as well as an offer for round 2 of the debate. The ball is in his court.
https://www.youtube.com/watch?v=HRdzk...
6 months ago (edited) | [YT] | 305
View 35 replies
Dr. Matthew Nagra, ND
I just launched YouTube Channel Memberships!
If you’ve enjoyed my videos and want to support the work I’m doing, memberships are one way to do that. Members get a few small perks like early access to some videos, member-only polls and updates, and priority replies to comments.
The main goal, though, is simply to give people who want to support the channel a way to help. I appreciate everyone who watches, shares, and engages with the content, and memberships are just another way to be part of the community.
Join this channel
youtube.com/channel/UCZQu95dIBQSvuP_0URa-jFA/join
8 months ago | [YT] | 48
View 1 reply
Dr. Matthew Nagra, ND
I joined ‪@davidramms‬ to debunk some of the anti-vegan (and pro-vegan) MYTHS! Check out the video!
8 months ago | [YT] | 30
View 0 replies
Dr. Matthew Nagra, ND
I just co-authored a new review on plant-based diets and choline!
Choline adequacy and health outcomes in vegetarian and vegan diets
www.academia.edu/3067-1345/2/4/10.20935/AcadNutr80…
10 months ago | [YT] | 70
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Dr. Matthew Nagra, ND
In this video, ‪@DoctorBoz‬ said she would like to debate me on nutrition. I have been trying to comment and take her up on that but my comments are not showing. I don’t know if she has pre-emptively hidden me from commenting or it’s a YouTube issue. That said, feel free to encourage her to follow through on this via commenting.
UPDATE: it was a YouTube issue and I am now able to comment. You can go and like/boost my comment.
10 months ago (edited) | [YT] | 20
View 0 replies
Dr. Matthew Nagra, ND
I got to participate in this debate hosted by ‪@jubilee‬! Go check it out (and like my comment to help boost it!)
11 months ago | [YT] | 15
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Dr. Matthew Nagra, ND
New podcast episode on everything protein! ‪@TheProofWithSimonHill‬
11 months ago | [YT] | 9
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