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55:58

This Isaac PRO Challenged Me to LOCKOUT Bingo. Again. Why did I accept.

Another Matt Playing Isaac  

Shared 4 weeks ago

120K views

29:03

Every Biblical/Religious reference in The Binding Of Isaac explained

The Night Archives

Shared 1 year ago

515K views

56:02

Beginner's Guide to the Binding of Isaac

Another Matt Playing Isaac  

Shared 3 months ago

155K views

56:20

My WEIRDEST Isaac Break to Date

Another Matt Playing Isaac  

Shared 2 weeks ago

112K views

1:06:48

Isaac CHARACTERS Tips & Tricks

Another Matt Playing Isaac  

Shared 2 years ago

522K views

1:01

The Binding of Isaac Texturepack top 10 #repentance #tboi #isaac

Robi_63

Shared 1 year ago

381K views

37:04

The ULTIMATE Isaac Quiz Ft @lazymattman

Another Matt Playing Isaac  

Shared 2 years ago

852K views

10:29

What Isaac Did To His Teacher In Class🤣🤣

Kat The Comedian malome kat  

Shared 2 years ago

1.7M views

35:22

Your Isaac Challenges are BREAKING My Game.

Another Matt Playing Isaac  

Shared 2 weeks ago

104K views

9:24

Isaac In class.. Malome Tebogo goes to school to reprimand Isaac..🤣🤣

Kat The Comedian malome kat  

Shared 1 year ago

217K views

10:04

Malome Kat Isaac and Lucas on firewood 🔥🪵🤣

Kat The Comedian malome kat  

Shared 7 months ago

90K views

1:01

The Binding of Isaac Texturepack top 10 #repentance #tboi #isaac

Robi_63

Shared 5 months ago

86K views

1:04:07

I Created Isaac's ULTIMATE Gameshow

Another Matt Playing Isaac  

Shared 3 weeks ago

519K views