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Ivabradine explained in 60 seconds! đź«€
Learn the mechanism of action, indications, contraindications, side effects, and drug interactions of ivabradine in this quick cardiology and pharmacology tutorial.
Ivabradine is a selective If (“funny”) current inhibitor that acts on the SA node and slows phase 4 depolarization, resulting in a reduced heart rate without directly reducing myocardial contractility.
In this Short, we cover: • Ivabradine mechanism of action
• If current / funny current
• SA node and phase 4 depolarization
• Ivabradine in HFrEF (heart failure with reduced ejection fraction)
• Chronic stable angina
• Beta-blocker contraindication or inadequate response
• Ivabradine contraindications
• Bradycardia and atrial fibrillation
• Phosphenes and visual side effects
• CYP3A4 drug interactions
đź§ USMLE Pharmacology & Cardiology Pearl:
If current → SA node → ↓ phase 4 depolarization → ↓ heart rate
Perfect for medical students, doctors, USMLE preparation, pharmacology revision, cardiology revision, and medical exam preparation.
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